Preheat the oven to 375°F(190°C). Line a baking sheet with parchment paper.
In a skillet over medium heat, brown the ground beef, crumbling it as it cooks. Drain any excess fat.
Season with garlic and onion powders, salt and pepper.
Add in half of the shredded cheddar (1/4 cup), and the cream cheese. Stir until incorporated.
Separate the biscuits. Place a pinch of the remaining shredded cheese in each biscuit and top with a spoonful of beef.
Fold the edges of the biscuit up over the filling and pinch to seal.
Place the buns, seam-side down, on the baking sheet.
Brush the tops with melted butter. Sprinkle on some parmesan cheese.
Bake for 12-15 minutes, until puffy and golden on top.
Garnish with more parmesan and fresh parsley.